Peripheral inflammation promotes brain tau transmission via disrupting blood–brain barrier

Abnormal aggregation of pathological tau protein is a neuropathological feature of Alzheimer’s disease (AD). In the AD patients, the abnormal tau accumulation first appeared in entorhinal cortex (EC) and then propagated to the hippocampus with microglia activation and inflammation, but the mechanism...

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Detalles Bibliográficos
Autores principales: Liu, Yanchao, Zhang, Shujuan, Li, Xiaoguang, Liu, Enjie, Wang, Xin, Zhou, Qiuzhi, Ye, Jinwang, Wang, Jian-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Aging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033313/
https://www.ncbi.nlm.nih.gov/pubmed/32043530
http://dx.doi.org/10.1042/BSR20193629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033313/
https://www.ncbi.nlm.nih.gov/pubmed/32043530
http://dx.doi.org/10.1042/BSR20193629

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