Nitrite elicits divergent NO-dependent signaling that associates with outcome in out of hospital cardiac arrest

Brain and heart injury cause most out-of-hospital cardiac arrest deaths but limited pharmacotherapy exists to protect these tissues. Nitrite is a nitric oxide precursor that is protective in pre-clinical models of ischemic injury and safe in Phase I testing. Protection may occur by cGMP generation v...

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Detalles Bibliográficos
Autores principales: Vitturi, Dario A., Maynard, Charles, Olsufka, Michele, Straub, Adam C., Krehel, Nick, Kudenchuk, Peter J., Nichol, Graham, Sayre, Michael, Kim, Francis, Dezfulian, Cameron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033352/
https://www.ncbi.nlm.nih.gov/pubmed/32087553
http://dx.doi.org/10.1016/j.redox.2020.101463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033352/
https://www.ncbi.nlm.nih.gov/pubmed/32087553
http://dx.doi.org/10.1016/j.redox.2020.101463

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