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Pharmacodynamic principles and the time course of immediate drug effects

This tutorial defines the principles of the concentration - effect relationship which are the basis of pharmacodynamics. The two key parameters of pharmacodynamics are the maximum response (Emax) and the concentration producing 50% of Emax (C(50)). The time course of effect is illustrated under the...

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Detalles Bibliográficos
Autor principal: Holford, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033401/
https://www.ncbi.nlm.nih.gov/pubmed/32095468
http://dx.doi.org/10.12793/tcp.2017.25.4.157