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Development of a simple and sensitive HPLC-MS/MS method for determination of diazepam in human plasma and its application to a bioequivalence study

We developed a simple, sensitive, and effective ultra-performance liquid chromatography/tandem mass spectrometry (HPLC-MS/MS) method with an electrospray ionization (ESI) interface in multiple reaction monitoring (MRM) and positive ion modes to determine diazepam concentrations in human plasma using...

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Detalles Bibliográficos
Autores principales: Kim, Do-Hyung, Cho, Ji-Yoon, Chae, Soo-In, Kang, Bo-Kyung, An, Tae-Gil, Shim, Wang-Seob, Noh, Young Su, Hwang, Se Jung, Chung, Eun Kyoung, Lee, Kyung-Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033404/
https://www.ncbi.nlm.nih.gov/pubmed/32095471
http://dx.doi.org/10.12793/tcp.2017.25.4.173