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Post lumbar puncture headache: Case report of a serious adverse event in first-in-human study

A lumbar puncture can be used to measure the concentrations of drugs and/or pharmacodynamic biomarkers during clinical trials of central nervous system drugs. We report a case of a post lumbar puncture headache (PLPH) in a first-in-human study, which was reported as a serious adverse event. A 20-yea...

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Detalles Bibliográficos
Autores principales: Shin, Wonsuk, Kim, Min-Kyoung, Kim, Jinkwon, Woo, Min-Hee, Cho, Doo-Yeon, Lim, Kyoung Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033405/
https://www.ncbi.nlm.nih.gov/pubmed/32095469
http://dx.doi.org/10.12793/tcp.2017.25.4.162