Allele-Selective Knockdown of MYH7 Using Antisense Oligonucleotides

Hundreds of dominant-negative myosin mutations have been identified that lead to hypertrophic cardiomyopathy, and the biomechanical link between mutation and disease is heterogeneous across this patient population. To increase the therapeutic feasibility of treating this diverse genetic population,...

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Detalles Bibliográficos
Autores principales: Anderson, Brian R., Jensen, Marianne L., Hagedorn, Peter H., Little, Sean C., Olson, Richard E., Ammar, Ron, Kienzle, Bernadette, Thompson, John, McDonald, Ivar, Mercer, Stephen, Vikesaa, Jonas, Nordbo, Bettina, Iben, Larry, Cao, Yang, Natale, Joanne, Dalton-Kay, Greg, Cacace, Angela, Hansen, Bo R., Hedtjärn, Maj, Koch, Troels, Bristow, Linda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033438/
https://www.ncbi.nlm.nih.gov/pubmed/32092825
http://dx.doi.org/10.1016/j.omtn.2020.01.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033438/
https://www.ncbi.nlm.nih.gov/pubmed/32092825
http://dx.doi.org/10.1016/j.omtn.2020.01.012

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