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Neoantigens in Hematologic Malignancies

T cell cancer neoantigens are created from peptides derived from cancer-specific aberrant proteins, such as mutated and fusion proteins, presented in complex with human leukocyte antigens on the cancer cell surface. Because expression of the aberrant target protein is exclusive to malignant cells, i...

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Detalles Bibliográficos
Autores principales: Biernacki, Melinda A., Bleakley, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033457/
https://www.ncbi.nlm.nih.gov/pubmed/32117272
http://dx.doi.org/10.3389/fimmu.2020.00121