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Gene Silencing of Transferrin-1 Receptor as a Potential Therapeutic Target for Human Follicular and Anaplastic Thyroid Cancer

Herein, we assess the gene expression changes activated in thyroid tumors through a computational approach, using the MapReduce algorithm. Through this predictive analysis, we identified the TfR1 gene as a critical mediator of thyroid tumor progression. Then, we investigated the effect of TfR1 gene...

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Detalles Bibliográficos
Autores principales: Campisi, Agata, Bonfanti, Roberta, Raciti, Giuseppina, Bonaventura, Gabriele, Legnani, Laura, Magro, Gaetano, Pennisi, Marzio, Russo, Giulia, Chiacchio, Maria Assunta, Pappalardo, Francesco, Parenti, Rosalba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033459/
https://www.ncbi.nlm.nih.gov/pubmed/32099899
http://dx.doi.org/10.1016/j.omto.2020.01.003