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Rheumatoid Arthritis Patients, Both Newly Diagnosed and Methotrexate Treated, Show More DNA Methylation Differences in CD4(+) Memory Than in CD4(+) Naïve T Cells
Background: Differences in DNA methylation have been reported in B and T lymphocyte populations, including CD4(+) T cells, isolated from rheumatoid arthritis (RA) patients when compared to healthy controls. CD4(+) T cells are a heterogeneous cell type with subpopulations displaying distinct DNA meth...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033478/ https://www.ncbi.nlm.nih.gov/pubmed/32117312 http://dx.doi.org/10.3389/fimmu.2020.00194 |