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Rheumatoid Arthritis Patients, Both Newly Diagnosed and Methotrexate Treated, Show More DNA Methylation Differences in CD4(+) Memory Than in CD4(+) Naïve T Cells

Background: Differences in DNA methylation have been reported in B and T lymphocyte populations, including CD4(+) T cells, isolated from rheumatoid arthritis (RA) patients when compared to healthy controls. CD4(+) T cells are a heterogeneous cell type with subpopulations displaying distinct DNA meth...

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Detalles Bibliográficos
Autores principales:	Guderud, Kari, Sunde, Line H., Flåm, Siri T., Mæhlen, Marthe T., Mjaavatten, Maria D., Lillegraven, Siri, Aga, Anna-Birgitte, Evenrød, Ida M., Norli, Ellen S., Andreassen, Bettina K., Franzenburg, Sören, Franke, Andre, Haavardsholm, Espen A., Rayner, Simon, Gervin, Kristina, Lie, Benedicte A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033478/ https://www.ncbi.nlm.nih.gov/pubmed/32117312 http://dx.doi.org/10.3389/fimmu.2020.00194

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