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Cytochrome P450-Based Drug-Drug Interactions of Vonoprazan In Vitro and In Vivo

BACKGROUND: Vonoprazan fumarate is a potassium-competitive acid blocker that was developed as a novel acid-suppressing drug for multiple indications. As a potential alternative to proton-pump inhibitors, the determination of the drug-drug interactions is vital for further applications. Probe drug co...

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Detalles Bibliográficos
Autores principales: Wang, Yiran, Wang, Changxiong, Wang, Shuanghu, Zhou, Quan, Dai, Dapeng, Shi, Jihua, Xu, Xue, Luo, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033572/
https://www.ncbi.nlm.nih.gov/pubmed/32116727
http://dx.doi.org/10.3389/fphar.2020.00053