High Glucose-Induced TRPC6 Channel Activation Decreases Glutamate Uptake in Rat Retinal Müller Cells

High glucose (HG) increases the production of reactive oxygen species (ROS), leading to decreased glutamate uptake in Müller cells. The transient receptor potential cation channel 6 (TRPC6) channel, an oxidative stress-sensitive Ca(2+)-permeable cationic channel, is readily detected in Müller cells...

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Detalles Bibliográficos
Autores principales: Ma, Mingming, Zhao, Shuzhi, Zhang, Jian, Sun, Tao, Fan, Ying, Zheng, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033573/
https://www.ncbi.nlm.nih.gov/pubmed/32116675
http://dx.doi.org/10.3389/fphar.2019.01668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033573/
https://www.ncbi.nlm.nih.gov/pubmed/32116675
http://dx.doi.org/10.3389/fphar.2019.01668

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