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MBOAT7-driven phosphatidylinositol remodeling promotes the progression of clear cell renal carcinoma

OBJECTIVE: The most common kidney cancer, clear cell renal cell carcinoma (ccRCC), is closely associated with obesity. The “clear cell” variant of RCC gets its name from the large lipid droplets that accumulate in the tumor cells. Although renal lipid metabolism is altered in ccRCC, the mechanisms a...

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Detalles Bibliográficos
Autores principales: Neumann, Chase K.A., Silver, Daniel J., Venkateshwari, Varadharajan, Zhang, Renliang, Traughber, C. Alicia, Przybycin, Christopher, Bayik, Defne, Smith, Jonathan D., Lathia, Justin D., Rini, Brian I., Brown, J. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033598/
https://www.ncbi.nlm.nih.gov/pubmed/32180553
http://dx.doi.org/10.1016/j.molmet.2020.01.011