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MBOAT7-driven phosphatidylinositol remodeling promotes the progression of clear cell renal carcinoma
OBJECTIVE: The most common kidney cancer, clear cell renal cell carcinoma (ccRCC), is closely associated with obesity. The “clear cell” variant of RCC gets its name from the large lipid droplets that accumulate in the tumor cells. Although renal lipid metabolism is altered in ccRCC, the mechanisms a...
Autores principales: | Neumann, Chase K.A., Silver, Daniel J., Venkateshwari, Varadharajan, Zhang, Renliang, Traughber, C. Alicia, Przybycin, Christopher, Bayik, Defne, Smith, Jonathan D., Lathia, Justin D., Rini, Brian I., Brown, J. Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033598/ https://www.ncbi.nlm.nih.gov/pubmed/32180553 http://dx.doi.org/10.1016/j.molmet.2020.01.011 |
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