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Resistance Evolution Against Antimicrobial Peptides in Staphylococcus aureus Alters Pharmacodynamics Beyond the MIC

Antimicrobial peptides (AMPs) have been proposed as a promising class of new antimicrobials partly because they are less susceptible to bacterial resistance evolution. This is possibly caused by their mode of action but also by their pharmacodynamic characteristics, which differ significantly from c...

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Detalles Bibliográficos
Autores principales: El Shazely, Baydaa, Yu, Guozhi, Johnston, Paul R., Rolff, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033599/
https://www.ncbi.nlm.nih.gov/pubmed/32117132
http://dx.doi.org/10.3389/fmicb.2020.00103