Cargando…

PRC1 Catalytic Activity Is Central to Polycomb System Function

The Polycomb repressive system is an essential chromatin-based regulator of gene expression. Despite being extensively studied, how the Polycomb system selects its target genes is poorly understood, and whether its histone-modifying activities are required for transcriptional repression remains cont...

Descripción completa

Detalles Bibliográficos
Autores principales: Blackledge, Neil P., Fursova, Nadezda A., Kelley, Jessica R., Huseyin, Miles K., Feldmann, Angelika, Klose, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033600/
https://www.ncbi.nlm.nih.gov/pubmed/31883950
http://dx.doi.org/10.1016/j.molcel.2019.12.001