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PRC1 Catalytic Activity Is Central to Polycomb System Function
The Polycomb repressive system is an essential chromatin-based regulator of gene expression. Despite being extensively studied, how the Polycomb system selects its target genes is poorly understood, and whether its histone-modifying activities are required for transcriptional repression remains cont...
Autores principales: | Blackledge, Neil P., Fursova, Nadezda A., Kelley, Jessica R., Huseyin, Miles K., Feldmann, Angelika, Klose, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033600/ https://www.ncbi.nlm.nih.gov/pubmed/31883950 http://dx.doi.org/10.1016/j.molcel.2019.12.001 |
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