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Tuft Cell Formation Reflects Epithelial Plasticity in Pancreatic Injury: Implications for Modeling Human Pancreatitis

Chronic pancreatitis, a known risk factor for the development of pancreatic ductal adenocarcinoma (PDA), is a serious, widespread medical condition characterized by inflammation, fibrosis, and acinar to ductal metaplasia (ADM). ADM is a cell type transdifferentiation event where pancreatic acinar ce...

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Detalles Bibliográficos
Autores principales: DelGiorno, Kathleen E., Naeem, Razia F., Fang, Linjing, Chung, Chi-Yeh, Ramos, Cynthia, Luhtala, Natalie, O’Connor, Carolyn, Hunter, Tony, Manor, Uri, Wahl, Geoffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033634/
https://www.ncbi.nlm.nih.gov/pubmed/32116793
http://dx.doi.org/10.3389/fphys.2020.00088