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Tuft Cell Formation Reflects Epithelial Plasticity in Pancreatic Injury: Implications for Modeling Human Pancreatitis
Chronic pancreatitis, a known risk factor for the development of pancreatic ductal adenocarcinoma (PDA), is a serious, widespread medical condition characterized by inflammation, fibrosis, and acinar to ductal metaplasia (ADM). ADM is a cell type transdifferentiation event where pancreatic acinar ce...
Autores principales: | DelGiorno, Kathleen E., Naeem, Razia F., Fang, Linjing, Chung, Chi-Yeh, Ramos, Cynthia, Luhtala, Natalie, O’Connor, Carolyn, Hunter, Tony, Manor, Uri, Wahl, Geoffrey M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033634/ https://www.ncbi.nlm.nih.gov/pubmed/32116793 http://dx.doi.org/10.3389/fphys.2020.00088 |
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