Sequence-dependent trafficking and activity of GDE2, a GPI-specific phospholipase promoting neuronal differentiation

GDE2 (also known as GDPD5) is a multispanning membrane phosphodiesterase with phospholipase D-like activity that cleaves select glycosylphosphatidylinositol (GPI)-anchored proteins and thereby promotes neuronal differentiation both in vitro and in vivo. GDE2 is a prognostic marker in neuroblastoma,...

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Detalles Bibliográficos
Autores principales: Salgado-Polo, Fernando, van Veen, Michiel, van den Broek, Bram, Jalink, Kees, Leyton-Puig, Daniela, Perrakis, Anastassis, Moolenaar, Wouter H., Matas-Rico, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033719/
https://www.ncbi.nlm.nih.gov/pubmed/31932507
http://dx.doi.org/10.1242/jcs.235044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033719/
https://www.ncbi.nlm.nih.gov/pubmed/31932507
http://dx.doi.org/10.1242/jcs.235044

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