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Involvement of Low‐Density Lipoprotein Receptor in the Pathogenesis of Pulmonary Hypertension

BACKGROUND: Recently, we and others have reported a causal role for oxidized lipids in the pathogenesis of pulmonary hypertension (PH). However, the role of low‐density lipoprotein receptor (LDL‐R) in PH is not known. METHODS AND RESULTS: We examined the role of LDL‐R in the development of PH and de...

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Detalles Bibliográficos
Autores principales: Umar, Soban, Ruffenach, Gregoire, Moazeni, Shayan, Vaillancourt, Mylene, Hong, Jason, Cunningham, Christine, Cao, Nancy, Navab, Sara, Sarji, Shervin, Li, Min, Lee, Lisa, Fishbein, Greg, Ardehali, Abbas, Navab, Mohamad, Reddy, Srinivasa T., Eghbali, Mansoureh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033825/
https://www.ncbi.nlm.nih.gov/pubmed/31914876
http://dx.doi.org/10.1161/JAHA.119.012063