Cytotoxicity of amide-linked local anesthetics on melanoma cells via inhibition of Ras and RhoA signaling independent of sodium channel blockade

BACKGROUND: Substantial clinical and preclinical evidence have indicated the association between amide-linked local anesthesia and the long-term outcomes of cancer patients. However, the potential effects of local anesthesia on cancer recurrence are inconclusive and the underlying mechanisms remain...

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Detalles Bibliográficos
Autores principales: Zheng, Qinghong, Peng, Xiaohong, Zhang, Yaqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033929/
https://www.ncbi.nlm.nih.gov/pubmed/32085741
http://dx.doi.org/10.1186/s12871-020-00957-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033929/
https://www.ncbi.nlm.nih.gov/pubmed/32085741
http://dx.doi.org/10.1186/s12871-020-00957-4

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