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lncRNA-PLACT1 sustains activation of NF-κB pathway through a positive feedback loop with IκBα/E2F1 axis in pancreatic cancer

BACKGROUND: The activation of NF-κB signaling pathway is regarded as the dominant process that correlates with tumorigenesis. Recently, increasing evidence shows that long noncoding RNAs (lncRNAs) play crucial roles in sustaining the NF-κB signaling pathway. However, the underlying mechanisms have n...

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Detalles Bibliográficos
Autores principales: Ren, Xiaofan, Chen, Changhao, Luo, Yuming, Liu, Mingyang, Li, Yuting, Zheng, Shangyou, Ye, Huilin, Fu, Zhiqiang, Li, Min, Li, Zhihua, Chen, Rufu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033942/
https://www.ncbi.nlm.nih.gov/pubmed/32085715
http://dx.doi.org/10.1186/s12943-020-01153-1