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Molecular and Coarse-Grained Modeling to Characterize and Optimize Dendrimer-Based Nanocarriers for Short Interfering RNA Delivery

[Image: see text] Dendrimer nanocarriers are unique hyper-branched polymers with biomolecule-like properties, representing a promising prospect as a nucleic acid delivery system. The design of effective dendrimer-based gene carriers requires considering several parameters, such as carrier morphology...

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Detalles Bibliográficos
Autores principales: Stojceski, Filip, Grasso, Gianvito, Pallante, Lorenzo, Danani, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033960/
https://www.ncbi.nlm.nih.gov/pubmed/32095720
http://dx.doi.org/10.1021/acsomega.9b03908