Sen1 Is Recruited to Replication Forks via Ctf4 and Mrc1 and Promotes Genome Stability

DNA replication and RNA transcription compete for the same substrate during S phase. Cells have evolved several mechanisms to minimize such conflicts. Here, we identify the mechanism by which the transcription termination helicase Sen1 associates with replisomes. We show that the N terminus of Sen1...

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Detalles Bibliográficos
Autores principales: Appanah, Rowin, Lones, Emma Claire, Aiello, Umberto, Libri, Domenico, De Piccoli, Giacomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034062/
https://www.ncbi.nlm.nih.gov/pubmed/32075754
http://dx.doi.org/10.1016/j.celrep.2020.01.087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034062/
https://www.ncbi.nlm.nih.gov/pubmed/32075754
http://dx.doi.org/10.1016/j.celrep.2020.01.087

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