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Sen1 Is Recruited to Replication Forks via Ctf4 and Mrc1 and Promotes Genome Stability
DNA replication and RNA transcription compete for the same substrate during S phase. Cells have evolved several mechanisms to minimize such conflicts. Here, we identify the mechanism by which the transcription termination helicase Sen1 associates with replisomes. We show that the N terminus of Sen1...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034062/ https://www.ncbi.nlm.nih.gov/pubmed/32075754 http://dx.doi.org/10.1016/j.celrep.2020.01.087 |