Cargando…
Vibrio pore-forming leukocidin activates pyroptotic cell death via the NLRP3 inflammasome
Cell death mechanisms are central to combat infections and to drive inflammation. The inflammasome controls infection through activation of caspase-1 leading to either IL-1β dependent inflammation, or pyroptotic cell death in infected cells. Hemolysins, which are pore-forming toxins (PFTs), alter th...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034064/ https://www.ncbi.nlm.nih.gov/pubmed/32013758 http://dx.doi.org/10.1080/22221751.2020.1720526 |