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Vibrio pore-forming leukocidin activates pyroptotic cell death via the NLRP3 inflammasome
Cell death mechanisms are central to combat infections and to drive inflammation. The inflammasome controls infection through activation of caspase-1 leading to either IL-1β dependent inflammation, or pyroptotic cell death in infected cells. Hemolysins, which are pore-forming toxins (PFTs), alter th...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034064/ https://www.ncbi.nlm.nih.gov/pubmed/32013758 http://dx.doi.org/10.1080/22221751.2020.1720526 |