Synthesis, anti-inflammatory, cytotoxic, and COX-1/2 inhibitory activities of cyclic imides bearing 3-benzenesulfonamide, oxime, and β-phenylalanine scaffolds: a molecular docking study

Cyclic imides containing 3-benzenesulfonamide, oxime, and β-phenylalanine derivatives were synthesised and evaluated to elucidate their in vivo anti-inflammatory and ulcerogenic activity and in vitro cytotoxic effects. Most active anti-inflammatory agents were subjected to in vitro COX-1/2 inhibitio...

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Detalles Bibliográficos
Autores principales: Abdel-Aziz, Alaa A.-M., El-Azab, Adel S., AlSaif, Nawaf A., Alanazi, Mohammed M., El-Gendy, Manal A., Obaidullah, Ahmad J., Alkahtani, Hamad M., Almehizia, Abdulrahman A., Al-Suwaidan, Ibrahim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034070/
https://www.ncbi.nlm.nih.gov/pubmed/32013633
http://dx.doi.org/10.1080/14756366.2020.1722120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034070/
https://www.ncbi.nlm.nih.gov/pubmed/32013633
http://dx.doi.org/10.1080/14756366.2020.1722120

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