Cargando…

Discovery of small molecule inhibitors of Leishmania braziliensis Hsp90 chaperone

Leishmaniasis is a neglected disease caused by the protozoa Leishmania ssp. Environmental differences found by the parasites in the vector and the host are translated into cellular stress, leading to the production of heat shock proteins (Hsp). These are molecular chaperones involved in the folding...

Descripción completa

Detalles Bibliográficos
Autores principales: Batista, Fernanda A. H., Ramos, Sérgio L., Tassone, Giusy, Leitão, Andrei, Montanari, Carlos A., Botta, Maurizio, Mori, Mattia, Borges, Júlio C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034072/
https://www.ncbi.nlm.nih.gov/pubmed/32048531
http://dx.doi.org/10.1080/14756366.2020.1726342