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Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels
Potassium ion conduction through open potassium channels is essential to control of membrane potentials in all cells. To elucidate the open conformation and hence the mechanism of K(+) ion conduction in the classic inward rectifier Kir2.2, we introduced a negative charge (G178D) at the crossing poin...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034095/ https://www.ncbi.nlm.nih.gov/pubmed/31744859 http://dx.doi.org/10.1085/jgp.201912422 |