C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors

NorA is the most studied efflux pump of Staphylococcus aureus and is responsible for high level resistance towards fluoroquinolone drugs. Although along the years many NorA efflux pump inhibitors (EPIs) have been reported, poor information is available about structure-activity relationship (SAR) aro...

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Detalles Bibliográficos
Autores principales: Felicetti, Tommaso, Mangiaterra, Gianmarco, Cannalire, Rolando, Cedraro, Nicholas, Pietrella, Donatella, Astolfi, Andrea, Massari, Serena, Tabarrini, Oriana, Manfroni, Giuseppe, Barreca, Maria Letizia, Cecchetti, Violetta, Biavasco, Francesca, Sabatini, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034129/
https://www.ncbi.nlm.nih.gov/pubmed/31992093
http://dx.doi.org/10.1080/14756366.2020.1719083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034129/
https://www.ncbi.nlm.nih.gov/pubmed/31992093
http://dx.doi.org/10.1080/14756366.2020.1719083

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