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Selective inhibitors for JNK signalling: a potential targeted therapy in cancer

c-Jun N-terminal kinase (JNK) signalling regulates both cancer cell apoptosis and survival. Emerging evidence show that JNK promoted tumour progression is involved in various cancers, that include human pancreatic-, lung-, and breast cancer. The pro-survival JNK oncoprotein functions in a cell conte...

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Detalles Bibliográficos
Autores principales: Wu, Qinghua, Wu, Wenda, Jacevic, Vesna, Franca, Tanos C. C., Wang, Xu, Kuca, Kamil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034130/
https://www.ncbi.nlm.nih.gov/pubmed/31994958
http://dx.doi.org/10.1080/14756366.2020.1720013