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Improved solubility, dissolution rate, and oral bioavailability of main biflavonoids from Selaginella doederleinii extract by amorphous solid dispersion

Amentoflavone, robustaflavone, 2″,3″-dihydro-3′,3‴-biapigenin, 3′,3‴-binaringenin, and delicaflavone are five major hydrophobic components in the total biflavonoids extract from Selaginella doederleinii (TBESD) that display favorable anticancer properties. The purpose of this study was to develop a...

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Detalles Bibliográficos
Autores principales: Chen, Bing, Wang, Xuewen, Zhang, Yanyan, Huang, Kangping, Liu, Hao, Xu, Dafen, Li, Shaoguang, Liu, Qicai, Huang, Jianyong, Yao, Hong, Lin, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034131/
https://www.ncbi.nlm.nih.gov/pubmed/32037895
http://dx.doi.org/10.1080/10717544.2020.1716876