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Murine Gut Microbiome Association With APOE Alleles

Background: Since APOE alleles represent the most impactful genetic risk factors for Alzheimer's disease (AD), their differential mechanism(s) of action are under intense scrutiny. APOE4 is robustly associated with increased AD risk compared to the neutral APOE3 and protective APOE2. APOE allel...

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Detalles Bibliográficos
Autores principales: Parikh, Ishita J., Estus, Janice L., Zajac, Diana J., Malik, Manasi, Maldonado Weng, Juan, Tai, Leon M., Chlipala, George E., LaDu, Mary Jo, Green, Stefan J., Estus, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034241/
https://www.ncbi.nlm.nih.gov/pubmed/32117315
http://dx.doi.org/10.3389/fimmu.2020.00200