Combination of multicomponent KA(2) and Pauson–Khand reactions: short synthesis of spirocyclic pyrrolocyclopentenones

The Cu-catalyzed multicomponent ketone–amine–alkyne (KA(2)) reaction was combined with a Pauson–Khand cycloaddition to give access of unprecedented constrained spirocyclic pyrrolocyclopentenone derivatives following a DOS couple-pair approach. The polyfunctional molecular scaffolds were tested on th...

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Detalles Bibliográficos
Autores principales: Innocenti, Riccardo, Lenci, Elena, Menchi, Gloria, Trabocchi, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034245/
https://www.ncbi.nlm.nih.gov/pubmed/32117477
http://dx.doi.org/10.3762/bjoc.16.23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034245/
https://www.ncbi.nlm.nih.gov/pubmed/32117477
http://dx.doi.org/10.3762/bjoc.16.23

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