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Combination of multicomponent KA(2) and Pauson–Khand reactions: short synthesis of spirocyclic pyrrolocyclopentenones
The Cu-catalyzed multicomponent ketone–amine–alkyne (KA(2)) reaction was combined with a Pauson–Khand cycloaddition to give access of unprecedented constrained spirocyclic pyrrolocyclopentenone derivatives following a DOS couple-pair approach. The polyfunctional molecular scaffolds were tested on th...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034245/ https://www.ncbi.nlm.nih.gov/pubmed/32117477 http://dx.doi.org/10.3762/bjoc.16.23 |