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Adenylate cyclase activator forskolin alleviates intracerebroventricular propionic acid-induced mitochondrial dysfunction of autistic rats

Neuronal mitochondrial dysfunction increases inflammatory mediators and leads to free radical generation and anti-oxidant enzymatic alterations, which are major neuropathological hallmarks responsible for autism. Mitochondrial dysfunction in autism is associated with decreased ATP levels due to redu...

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Detalles Bibliográficos
Autores principales: Mehan, Sidharth, Rahi, Saloni, Tiwari, Aarti, Kapoor, Tarun, Rajdev, Kajal, Sharma, Ramit, Khera, Himanshi, Kosey, Sourabh, Kukkar, Umesh, Dudi, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034277/
https://www.ncbi.nlm.nih.gov/pubmed/31823895
http://dx.doi.org/10.4103/1673-5374.270316