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Interleukin 1 receptor antagonist (IL1RN) gene variants predict radiographic severity of knee osteoarthritis and risk of incident disease

OBJECTIVE: In these studies, we examined the association of single nucleotide polymorphisms (SNPs) of the IL1RN gene with radiographic severity of symptomatic knee osteoarthritis (SKOA) and the risk of incident OA. We also explored these genetic polymorphisms in patients with new onset rheumatoid ar...

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Detalles Bibliográficos
Autores principales: Attur, Mukundan, Zhou, Hua, Samuels, Johathan, Krasnokutsky, Svetlana, Yau, Michelle, Scher, Jose U, Doherty, Michael, Wilson, Anthony G, Bencardino, Jenny, Hochberg, Marc, Jordan, Joanne M, Mitchell, Braxton, Kraus, Virginia B, Abramson, Steven B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034355/
https://www.ncbi.nlm.nih.gov/pubmed/31852669
http://dx.doi.org/10.1136/annrheumdis-2019-216055