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Cytokine mRNA Degradation in Cardiomyocytes Restrains Sterile Inflammation in Pressure-Overloaded Hearts

BACKGROUND: Proinflammatory cytokines play an important role in the pathogenesis of heart failure. The mechanisms responsible for maintaining sterile inflammation within failing hearts remain poorly defined. Although transcriptional control is important for proinflammatory cytokine gene expression,...

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Detalles Bibliográficos
Autores principales: Omiya, Shigemiki, Omori, Yosuke, Taneike, Manabu, Murakawa, Tomokazu, Ito, Jumpei, Tanada, Yohei, Nishida, Kazuhiko, Yamaguchi, Osamu, Satoh, Takashi, Shah, Ajay M., Akira, Shizuo, Otsu, Kinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034406/
https://www.ncbi.nlm.nih.gov/pubmed/31931613
http://dx.doi.org/10.1161/CIRCULATIONAHA.119.044582