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CRISPRpic: fast and precise analysis for CRISPR-induced mutations via prefixed index counting

Analysis of CRISPR-induced mutations at targeted locus can be achieved by polymerase chain reaction amplification followed by parallel massive sequencing. We developed a novel algorithm, named as CRISPRpic, to analyze the sequencing reads for the CRISPR experiments via counting exact-matching and pa...

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Detalles Bibliográficos
Autores principales: Lee, HoJoon, Chang, Howard Y, Cho, Seung Woo, Ji, Hanlee P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034628/
https://www.ncbi.nlm.nih.gov/pubmed/32118203
http://dx.doi.org/10.1093/nargab/lqaa012