IGREX for quantifying the impact of genetically regulated expression on phenotypes

By leveraging existing GWAS and eQTL resources, transcriptome-wide association studies (TWAS) have achieved many successes in identifying trait-associations of genetically regulated expression (GREX) levels. TWAS analysis relies on the shared GREX variation across GWAS and the reference eQTL data, w...

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Detalles Bibliográficos
Autores principales: Cai, Mingxuan, Chen, Lin S, Liu, Jin, Yang, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Standard Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034630/
https://www.ncbi.nlm.nih.gov/pubmed/32118202
http://dx.doi.org/10.1093/nargab/lqaa010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034630/
https://www.ncbi.nlm.nih.gov/pubmed/32118202
http://dx.doi.org/10.1093/nargab/lqaa010

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