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Effect of dipeptidyl peptidase-4 inhibitors on cisplatin-induced acute nephrotoxicity in cancer patients with diabetes mellitus: A retrospective study

BACKGROUND: Cisplatin is a highly effective chemotherapeutic agent. However, acute kidney injury (AKI) limits its subsequent use, resulting in poor cancer prognosis. Dipeptidyl peptidase-4 (DPP-4) inhibitors have been reported to attenuate cisplatin-induced AKI in animal models, but the effect in hu...

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Detalles Bibliográficos
Autores principales: Iwakura, Takamasa, Fukasawa, Hirotaka, Kitamura, Atsushi, Ishibuchi, Kento, Yasuda, Hideo, Furuya, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034844/
https://www.ncbi.nlm.nih.gov/pubmed/32084231
http://dx.doi.org/10.1371/journal.pone.0229377