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Cigarette smoke downregulates Nur77 to exacerbate inflammation in chronic obstructive pulmonary disease (COPD)

Cigarette smoke (CS) contains multiple gaseous and particulate materials that can cause lung inflammation, and smoking is the major cause of chronic obstructive pulmonary disease (COPD). We sought to determine the mechanisms of how CS triggers lung inflammation. Nur77, a nuclear hormone receptor bel...

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Detalles Bibliográficos
Autores principales: Reddy, Aravind T., Lakshmi, Sowmya P., Banno, Asoka, Jadhav, Shantanu Krishna, Pulikkal Kadamberi, Ishaque, Kim, Seong C., Reddy, Raju C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034866/
https://www.ncbi.nlm.nih.gov/pubmed/32084204
http://dx.doi.org/10.1371/journal.pone.0229256