Oligoclonal IgG antibodies in multiple sclerosis target patient-specific peptides

IgG oligoclonal bands (OCBs) are present in the cerebrospinal fluid (CSF) of more than 95% of patients with multiple sclerosis (MS), and are considered to be the immunological hallmark of disease. However, the target specificities of the IgG in MS OCBs have remained undiscovered. Nevertheless, evide...

Descripción completa

Detalles Bibliográficos
Autores principales: Graner, Michael, Pointon, Tiffany, Manton, Sean, Green, Miyoko, Dennison, Kathryn, Davis, Mollie, Braiotta, Gino, Craft, Julia, Edwards, Taylor, Polonsky, Bailey, Fringuello, Anthony, Vollmer, Timothy, Yu, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034880/
https://www.ncbi.nlm.nih.gov/pubmed/32084151
http://dx.doi.org/10.1371/journal.pone.0228883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034880/
https://www.ncbi.nlm.nih.gov/pubmed/32084151
http://dx.doi.org/10.1371/journal.pone.0228883

Ejemplares similares