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Oligoclonal IgG antibodies in multiple sclerosis target patient-specific peptides

IgG oligoclonal bands (OCBs) are present in the cerebrospinal fluid (CSF) of more than 95% of patients with multiple sclerosis (MS), and are considered to be the immunological hallmark of disease. However, the target specificities of the IgG in MS OCBs have remained undiscovered. Nevertheless, evide...

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Detalles Bibliográficos
Autores principales: Graner, Michael, Pointon, Tiffany, Manton, Sean, Green, Miyoko, Dennison, Kathryn, Davis, Mollie, Braiotta, Gino, Craft, Julia, Edwards, Taylor, Polonsky, Bailey, Fringuello, Anthony, Vollmer, Timothy, Yu, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034880/
https://www.ncbi.nlm.nih.gov/pubmed/32084151
http://dx.doi.org/10.1371/journal.pone.0228883

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