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The acid-base-nucleophile catalytic triad in ABH-fold enzymes is coordinated by a set of structural elements

The alpha/beta-Hydrolases (ABH) are a structural class of proteins that are found widespread in nature and includes enzymes that can catalyze various reactions in different substrates. The catalytic versatility of the ABH fold enzymes, which has been a valuable property in protein engineering applic...

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Detalles Bibliográficos
Autores principales: Denesyuk, Alexander, Dimitriou, Polytimi S., Johnson, Mark S., Nakayama, Toru, Denessiouk, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034887/
https://www.ncbi.nlm.nih.gov/pubmed/32084230
http://dx.doi.org/10.1371/journal.pone.0229376