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The acid-base-nucleophile catalytic triad in ABH-fold enzymes is coordinated by a set of structural elements
The alpha/beta-Hydrolases (ABH) are a structural class of proteins that are found widespread in nature and includes enzymes that can catalyze various reactions in different substrates. The catalytic versatility of the ABH fold enzymes, which has been a valuable property in protein engineering applic...
Autores principales: | Denesyuk, Alexander, Dimitriou, Polytimi S., Johnson, Mark S., Nakayama, Toru, Denessiouk, Konstantin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034887/ https://www.ncbi.nlm.nih.gov/pubmed/32084230 http://dx.doi.org/10.1371/journal.pone.0229376 |
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