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A live auxotrophic vaccine confers mucosal immunity and protection against lethal pneumonia caused by Pseudomonas aeruginosa

Pseudomonas aeruginosa is one of the leading causes of nosocomial pneumonia and its associated mortality. Moreover, extensively drug-resistant high-risk clones are globally widespread, presenting a major challenge to the healthcare systems. Despite this, no vaccine is available against this high-con...

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Detalles Bibliográficos
Autores principales: Cabral, Maria P., Correia, Alexandra, Vilanova, Manuel, Gärtner, Fátima, Moscoso, Miriam, García, Patricia, Vallejo, Juan A., Pérez, Astrid, Francisco-Tomé, Mónica, Fuentes-Valverde, Víctor, Bou, Germán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034913/
https://www.ncbi.nlm.nih.gov/pubmed/32040500
http://dx.doi.org/10.1371/journal.ppat.1008311