Cargando…

Cell-autonomous light sensitivity via Opsin3 regulates fuel utilization in brown adipocytes

Opsin3 (Opn3) is a transmembrane heptahelical G protein–coupled receptor (GPCR) with the potential to produce a nonvisual photoreceptive effect. Interestingly, anatomical profiling of GPCRs reveals that Opn3 mRNA is highly expressed in adipose tissue. The photosensitive functions of Opn3 in mammals...

Descripción completa

Detalles Bibliográficos
Autores principales: Sato, Mari, Tsuji, Tadataka, Yang, Kunyan, Ren, Xiaozhi, Dreyfuss, Jonathan M., Huang, Tian Lian, Wang, Chih-Hao, Shamsi, Farnaz, Leiria, Luiz O., Lynes, Matthew D., Yau, King-Wai, Tseng, Yu-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034924/
https://www.ncbi.nlm.nih.gov/pubmed/32040503
http://dx.doi.org/10.1371/journal.pbio.3000630